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UDG (Uracil-DNA Glycosylase) catalyses and hydrolyses uracil base and N- glycosidic bond of the sugar phosphate skeleton which belong to single or double-stranded DNA containing dU. Thus, free uracils are released and the base-free sites are dissociated easily by hydrolysis.
Heat-labile UDG steming from psychrophilic marine bacterium, is sensitive to high temperature and therefore inactivates enzymes irreversibly when temperature over 50°C, which is suitable for PCR/QPCR, RT- PCR /RT-QPCR system.
Brand: Vazyme Biotech.